Prof.Dr. OYA ORUN
Tıp Fakültesi / Temel Tıp Bilimleri Bölümü

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Marmara Üniversitesi - Tıp Fakültesi / Temel Tıp Bilimleri Bölümü / Oda No (Belirtilmemiş)
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YAYINLAR & ESERLER
MAKALELER
ULUSLARARASI
SCI, SSCI, AHCI İNDEKSLERİNE GİREN DERGİLERDE YAYINLANAN MAKALELER
1. SERAKINCI NEDİME,MEGA TİBER PINAR,ORUN OYA. Chromatin modifications of hTERT gene in hTERT-immortalized human mesenchymal stem cells upon exposure to radiation. European Journal of Medical Genetics. Cilt 61. sf 288-293, 2018. (Yayına Ulaşmak İçin Tıklayınız)
2. ORUN OYA. RNF7 knockdown inhibits prostate cancer tumorigenesis by induction of apoptosis and inactivation of ERK1 2 pathway. Scientific Reports. 2016.
3. ORUN OYA,MEGA TİBER PINAR. FRET-based characterization of K264A, D345A, and Y335Amutants in the human dopamine transporter. TURKISH JOURNAL OF BIOLOGY. Cilt 41. sf 378-387, 2017. (Yayına Ulaşmak İçin Tıklayınız)
4. Ozden S,Ozgen Z,Kilinc O,Oncel M,Gul AE,Karadayi M,ORUN OYA,KAN BEKİ,Serakinci N. Prognostic role of sensitive to apoptosis gene expression in rectal cancer. World J Gastroenterol. Cilt 17. sf 4905-4910, 2011.
5. ORUN OYA,Serakinci Nedime,MEGA TİBER PINAR. Partial knockdown of TRF2 increase radiosensitivity of human mesenchymal stem cells. International Journal of Biological Macromolecules. 2016. (Yayına Ulaşmak İçin Tıklayınız)
6. ORUN OYA. SAG Rbx2 dependent neddylation regulates T cell responses. The American Journal of Pathology. 2015.
7. Yılmaz Özgür,Özbaş Turan Suna,Akbuğa Jülide,MEGA TİBER PINAR,ORUN OYA,Supuran Claudiu T,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ. Synthesis of pro apoptotic indapamide derivatives as anticancer agents. Journal of Enzyme Inhibition and Medicinal Chemistry. Cilt 30. sf 967-980, 2015. (Yayına Ulaşmak İçin Tıklayınız)
8. Özden Sevgi,MEGA TİBER PINAR,Ozgen Zerrin,Ozyurt Hazan,Serakinci Nedime,ORUN OYA. Expression of TRF2 and its prognostic relevance in advanced stage cervical cancer patients. Biological Research. Cilt 47. sf 61-, 2014. (Yayına Ulaşmak İçin Tıklayınız)
9. Kucukguzel Guniz,Koc D,Cikla Suzgun Pelin,Ozsavci D,Bingol Ozakpinar O,MEGA TİBER PINAR,ORUN OYA,Erzincan P,Sag Erdem S,Sahin F. Synthesis of Tolmetin Hydrazide Hydrazones and Discovery of a Potent Apoptosis Inducer in Colon Cancer Cells. Archiv der Pharmazie. Cilt 348. sf 730-742, 2015. (Yayına Ulaşmak İçin Tıklayınız)
10. ORUN OYA. İnsan dopamin taşıyıcısında FRET çalışmalarında kullanabilmek amacıyla floresan proteinlerle işaretlenebilecek işlevsel bölgelerinin belirlenmesi. J Neurological Sciences (Turkish). sf 287-, 2006.
11. CONTUK GAZİ,ORUN OYA,Demiralp-Ekşioğlu Emel,ERCAN FERİHA. Morphological alterations and distribution of occludin in rat testes after bilateral vasectomy. Acta Histochemica. Cilt 114. sf 244-251, 2012. (Yayına Ulaşmak İçin Tıklayınız)
12. ORUN OYA,Rasmussen Soren FR,Gether Ulrik. Introducing tetraCys motifs at two different sites results in a functional dopamine transporter. Acta Biologica Hungarica. Cilt 60. sf 15-25, 2009.
13. CABADAK HÜLYA,ORUN OYA,NACAR CEVDET,Dogan Yuksel,Guneysel Ozlem,FAK ALİ SERDAR,KAN BEKİ. G protein beta3 subunit polymorphisms C825T C1429T and G5177A in Turkish subjects with essential hypertension. Cl'n Exp Hypert. Cilt 33. sf 202-208, 2011.
14. Toklu Hale,KABASAKAL LEVENT,İMERYÜZ NEŞE,KAN BEKİ,ÇELİKEL ÇİĞDEM,ÇETİNEL ŞULE,ORUN OYA,YÜKSEL MERAL,Dulger Fatma. A study comparing the efficacy of antimicrobial agents versus enzyme P gp inducers in the treatment of 2 4 6 trinitrobenzenesulfonic acid induced colitis in rats. J Physiol Pharmacol. Cilt 64. sf 439-451, 2013.
15. Aydın Sevil,Kaushik Basu Neerja,Özbaş Turan Suna,Akbuğa Jülide,MEGA TİBER PINAR,ORUN OYA,Gurukumar K R,Basu Amartya,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ. Synthesis of 1 aroyl 3 5 dimethyl 1H pyrazoles as Anti HCV and Anticancer Agents. Letters in Drug Design & Discovery. Cilt 11. sf 121-131, 2014.
16. Oktay Sule,CABADAK HÜLYA,Iskender Ece,Goren Zafer,Caliskan Esen,ORUN OYA,Aslan Nuray,Karaalp Atilla,Tolun Asli,Ulusoy Nefise Barlas,Levey Allen,El Fakahany Esam E,KAN BEKİ. Evidence for the presence of muscarinic M2 and M4 receptors in guinea pig gallbladder smooth muscle. Journal of Autonomic Pharmacology. Cilt 18. sf 195-204, 1998.
17. MEGA TİBER PINAR,Baloglu Latife,Ozden Sevgi,Ozgen Zerrin,Ozyurt Hazan,Eren Makbule,ORUN OYA. The association of apoptotic protein expressions SAG p73 and p53 with prognosis in cervical carcinoma. Onco Targets and Therapy. Cilt 7. sf 2161-2168, 2014.
18. ORUN OYA,MEGA TİBER PINAR,SEZERMAN OSMAN UĞUR,SEVERCAN ŞEFAETTİN,KAN BEKİ,NACAR CEVDET. Structural characterization of recombinant bovine Go alpha byspectroscopy and homology modeling. SPECTROSCOPY-BIOMEDICAL APPLICATIONS. Cilt 26. sf 213-229, 2011.
19. MEGA TİBER PINAR,ORUN OYA,KOCAKAYA OZAN,CABADAK HÜLYA,NACAR CEVDET,FAK ALİ SERDAR,KAN BEKİ. Polymorphisms with Cardiovascular Parameters in a Turkish Population with Essential Hypertension. Experimental and Clinical Cardiology. Cilt 20. sf 4604-4612, 2014.
20. ORUN OYA,CABADAK HÜLYA,MEGA TİBER PINAR,Dogan Y,Guneysel O,FAK ALİ SERDAR,KAN BEKİ. Investigation of the association between dopamine D1 gene polymorphisms and essential hypertension in a group of Turkish subjects. Clinical and Experimental Hypertension. Cilt 33. sf 418-421, 2011.
21. Petoukhov MV,Svergun Dimitri,Koch Michel HJ,SAYERS ZEHRA,KAN BEKİ,ORUN OYA. Structural characterization of T protein of the Escherichia coli glycine cleavage system by X ray small angle scattering. Cellular and Molecular Biology. Cilt 49. sf 453-459, 2003.
22. Serakinci Nedime,ORUN OYA,MEGA TİBER PINAR. 423 Epigenetic effects of radiation on hTERT immortalized mesenchymal stem cells. European Journal of Cancer. Cilt 50. sf 101-, 2014. (Yayına Ulaşmak İçin Tıklayınız)
23. MEGA TİBER PINAR,ORUN OYA,Serakinci Nedime. 253 Expression of TRF2 and its prognostic relevance in advanced stage cervical cancer patients. European Journal of Cancer. Cilt 50. sf 59-60, 2014. (Yayına Ulaşmak İçin Tıklayınız)
24. AYKAÇ ASLI,ÖZBEYLİ DİLEK,UNCU MURAT MUSTAFA,ERTAŞ BÜŞRA,KILINÇ OLCA,ŞEN ALİ,ORUN OYA,ŞENER GÖKSEL. Evaluation of the protective effect of Myrtus communis in scopolamine-induced Alzheimer model through cholinergic receptors. Gene. Cilt 689. sf 194-201, 2019. (Yayına Ulaşmak İçin Tıklayınız)
DİĞER DERGİLERDE YAYIMLANAN MAKALELER
1. KOÇYİĞİT SEVİNÇ SEVGİ,ORUN OYA,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ. Anti-Cancer Acitivity of Etodolac and Its Derivatives on Prostate and Colorectal Cancer Cell Lines. Proceedings 2018. Cilt 2. sf 1573-, 2018. (Yayına Ulaşmak İçin Tıklayınız)
2. ORUN OYA. Roles of catecholamine related polymorphisms in hypertension. World Journal of Hypertension. Cilt 6. sf 41-, 2016. (Yayına Ulaşmak İçin Tıklayınız)
3. ORUN OYA,MEGA TİBER PINAR. Determination of spatial proximity between the N terminus and cocaine binding site of the dopamine transporter by FRET. Marmara Medical Journal. Cilt 28. sf 123-, 2015. (Yayına Ulaşmak İçin Tıklayınız)
ULUSAL
SCI, SSCI, AHCI İNDEKSLERİNE GİREN DERGİLERDE YAYINLANAN MAKALELER
1. ORUN OYA,KAN BEKİ. Goalfa cDNA sının pTrcHis sistemine alt klonlanması. Türk Biyokimya Dergisi. sf 8-, 2003.
DİĞER DERGİLERDE YAYIMLANAN MAKALELER
1. ORUN OYA. Lipopolisakkarit Sinyal Iletisinde mTOR un Rolu. Marmara Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2015.
KİTAPLAR
ULUSLARARASI
BİLİMSEL KİTAP
KİTAP BÖLÜMÜ
1. ORUN OYA,MEGA TİBER PINAR,KOÇYİĞİT SEVİNÇ SEVGİ, Nonsteroidal Anti-Inflammatory Drugs, Rijeka. 2017. (Yayına Ulaşmak İçin Tıklayınız)
EDİTÖRLÜKLER
Henüz içerik girilmemiş.
BİLDİRİLER
ULUSLARARASI
1. KOÇYİĞİT SEVİNÇ SEVGİ,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ,ORUN OYA, "CHARACTERIZATION OF THE EFFECT OF SEVERAL ETODOLAC DERIVATIVES ON CANCER CELL LINES", First International Cell Death Research Congress, 2016.
2. Yonar Kaplan Pelin,KOÇYİĞİT SEVİNÇ SEVGİ,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ,ORUN OYA, "ANTI CANCER ACITIVITY OF A HYDRAZONE DERIVATIVE OF ETODOLAC IN K562 LEUKEMIA CELL LINES", First International Cell Death Research Congress, 2016.
3. MEGA TİBER PINAR,KOÇYİĞİT SEVİNÇ SEVGİ,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ,ORUN OYA, "Effects of etodolac derivative compound SGK 216 on oxidative stress induced cellapoptosis in human leukemeia cell line", The World Congress of Oxidative Stress, Calcium Signaling and TRP channels, 2016.
4. ORUN OYA, "The role of TRF2 a shelterin protein on radiosensitivity of cancer stem cells", EACR- Sponsored 3rd Anticancer Agent Development Congress, 2015. (Yayına Ulaşmak İçin Tıklayınız)
5. MEGA TİBER PINAR,Avberk Sera,ORUN OYA,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Proliferative effects of two etodolac derivatives SGK 205 and SGK 216 on K562 leukemia cell line", EACR- Sponsored 3rd Anticancer Agent Development Congress, 2015.
6. ORUN OYA,KOÇYİĞİT SEVGİ,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Proliferative effects of two etodolac derivatives SGK 206 and SGK 242 on breast cancer cell lines", EACR- Sponsored 3rd Anticancer Agent Development Congress, 2015.
7. ORUN OYA,Avberk Sera,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Apoptotic effects of two etodolac derivatives SGK 205 and SGK 216 on K562 leukemia cell line", ISOPS 11 th International Symposium on Pharmaceutical Sciences, 2015.
8. ORUN OYA,MEGA TİBER PINAR,SERAKINCI NEDİME, "Epigenetic effects of radiation on hTERT immortalized mesenchymal stem cells", European Journal of Cancer , 23rd Biennal Cancer Research Proceedings Book, 2014.
9. ORUN OYA,Özden Sevgi,MEGA TİBER PINAR,SERAKINCI NEDİME,Özgen Zerrin,Özyurt Hazan, "Expression of TRF2 and its prognostic relevance in advanced stage cervical cancer patients", European Journal of Cancer 23rd Biennal Cancer Research Proceedings Book, 2014.
10. ORUN OYA,MEGA TİBER PINAR,ÇANKAYA TUFAN,SERAKINCI NEDİME, "Effect of siTRF2 knockdown a shelterin protein on the radiosensitivity of telomerase immortalised human mesenchymal stem cells", European Journal of Human Genetics, 2013.
11. MEGA TİBER PINAR,Baloğlu Latife,Özden Sevgi,ORUN OYA, "The association of apoptotic protein expressions SAG p73 and p53 with prognosis in cervical carcinoma", European Human Genetics Conference, 2013.
12. MEGA TİBER PINAR,Baloğlu Latife,Özden Sevgi,ORUN OYA, "Correlation between the tumoral expression of SAG RBX ROC2 E3 ubiquitin ligase and local control in cervical cancer patients", FEBS Special Meeting, 2012.
13. MEGA TİBER PINAR,ORUN OYA,Aydın S,TURAN SUNA,AKBUĞA FATMA JULİDE,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Discovery of a potent apoptosis inducer in K 562 cancer cell line", 10th International Symposium on Pharmaceutical Sciences, 2012.
14. ORUN OYA,Özden Sevgi,Özyurt Hazan,Özgen Zerrin,ÖNCEL MUSTAFA,KILINÇ OLCA,KAN BEKİ, "The role of SAG as a prognostic factor on radio chemotherapy in patients with advanced colorectal cancer", 3rd International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium Signaling and TRP channels, 2010.
15. Özden Sevgi,ORUN OYA,Özyurt Hazan,Özgen Zerrin,ÖNCEL MUSTAFA,KAN BEKİ, "Effects of sensitive to apoptosis gene SAG and p73 genes on radiotherapy and or chemotherapy", ESTRO 27, 2008.
16. MEGA TİBER PINAR,NACAR CEVDET,ORUN OYA,SEZERMAN OSMAN UĞUR,KAN BEKİ, "Purification characterization and modeling of recombinant Goalpha protein", Gordon Research Conferences, Phosphorylation & G-Protein Mediated Signaling Networks, 2007.
17. ORUN OYA,Rasmussen SGFR,Cha JH,Newman AH,Javitch Jonathan,Gether Ulrik, "N terminal conformational changes of dopamine transporter determined by FRET analysis", 31st FEBS Congress, 2006.
18. MEGA TİBER PINAR,NACAR CEVDET,ORUN OYA,KAN BEKİ, "Production of recombinant Go alpha protein using pQE 80 expression vector system", 31st FEBS Congress, 2006.
19. MEGA TİBER PINAR,ORUN OYA,KAN BEKİ, "Subcloning of Goalpha cDNA into pTrcHis system", 1st Congress of Molecular Medicine, 2005.
20. MEGA TİBER PINAR,NACAR CEVDET,ORUN OYA,Crossett Ben,Keith Karen,Brown Katherine,KAN BEKİ, "Attempts for proper folding of recombinant Goalpha protein after inclusion body purification", 30th FEBS Congress, 2005.
21. KAN BEKİ,ORUN OYA,Crossett Ben,NACAR CEVDET,NACAR CEVDET,SAYERS ZEHRA,SAYERS ZEHRA,Koch Michel,Brown Katherine, "Cloning of Goalpha and optimization of Goalpha GST fusion protein expression", The 7th IUBMB Conference, Receptor-Ligand Interactions, 2002.
22. ORUN OYA,Crossett Ben,NACAR CEVDET,SAYERS ZEHRA,Koch Michel,KAN BEKİ,Brown Katherine, "Purification of Glutathione S Transferase Fusion Go alpha Protein", Biophysics and Modelling of 7-Transmembrane Receptors, 2001.
23. ORUN OYA,KAN BEKİ,Koch Michel,SAYERS ZEHRA, "Partial purification and characterization of Goalfa", 10th International Conference on Second Messengers and Phosphoproteins, 1998.
24. KAN BEKİ,CABADAK HÜLYA,ORUN OYA,Oktay Şule,TOLUN ASLIHAN,TOLUN ASLIHAN,Ulusoy Nefise Barlas, "Characterization of muscarinic receptor subtypes in guinea pig gallbladder", XIIth International Biophysics Congress, 1996.
25. KILINÇ OLCA,MEGA TİBER PINAR,ORUN OYA,KOÇYİĞİT SEVİNÇ SEVGİ, "Anticancer activity of Rosemary Officinalis L. essential oil in ovarian cancer cell line", 1.International Health Sciences Congress, 2017.
26. KOÇYİĞİT SEVİNÇ SEVGİ,ORUN OYA,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Apoptotic Effect of Etodolac and its derivativeson Breast Cancer Cell line", International Meeting on Education and Research in Health Sciences, 2017.
27. YAŞAYAN GÖKÇEN,MEGA TİBER PINAR,ORUN OYA, "Preparation and Characterization Studies of Nanotextured Polycaprolactone Scaffolds", 13th Nanoscience and Nanotechnology Conference, 2017.
28. YAŞAYAN GÖKÇEN,ORUN OYA,MEGA TİBER PINAR,KOÇYİĞİT SEVİNÇ SEVGİ, "Modulation of Cancer Cell Behavior by Nanotexturing", International Meeting on EducationResearch in Health Sciences, 2017. (Yayına Ulaşmak İçin Tıklayınız)
29. ÇETİN EMEL,Karaböce Baki,KILINÇ OLCA,ORUN OYA, "Biological Effects of HIFU on HT-29 Colon Cancer Cell Lines", 2018 IEEE International Symposium on Medical Measurements and Applications (MeMeA), Rome, Italy, 2018. (Yayına Ulaşmak İçin Tıklayınız)
30. Karadeniz Melike,MEGA TİBER PINAR,ORUN OYA, "Determination effects of diosgenin and dactolisib in breast cancer cell lines", 30th Annual Biophysics Congress (International), 2018.
31. MEGA TİBER PINAR,ORUN OYA,KILINÇ OLCA,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Investigation of apoptotic gene expressions for two novel hydrazide derivatives of etodolac in K562 leukemia cell line", 30th Annual Biophysics Congress (International), 2018.
32. KOÇYİĞİT SEVİNÇ SEVGİ,ORUN OYA,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Apoptotic effect of etodolac and its derivative on breast cancer cell line", International Congress on Biological and Medical Sciences 2018, Niğde, 2018. (Yayına Ulaşmak İçin Tıklayınız)
33. BİRGÜL KAAN,Ub Abdullahi Ibrahim,çuhadar ozan,KOÇYİĞİT SEVİNÇ SEVGİ,MEGA TİBER PINAR,ORUN OYA,yılmaz özgür,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Synthesis and Molecular Modeling of New (S)-Naproxen Thioethers as Possible Breast Cancer Agents", 6th International BAU Drug Design Congress, 2018.
34. KOÇYİĞİT SEVİNÇ SEVGİ,MEGA TİBER PINAR,ORUN OYA, "Cytotoxic effects of etodolac in breast cancer cell cultures", IVEK 3rd International Convention of Pharmaceuticals and Pharmacies, İSTANBUL, 2017.
35. KOÇYİĞİT SEVİNÇ SEVGİ,MEGA TİBER PINAR,ORUN OYA, "Gene regulations upon etodolac induced apoptosis in breast cancer cell cultures", IVEK 3rd International Convention of Pharmaceuticals and Pharmacies, İSTANBUL, 2017.
36. KOÇYİĞİT SEVİNÇ SEVGİ,MEGA TİBER PINAR,ORUN OYA, "APOPTOTIC EFFECT OF GINGER (zingiber officinale) ON K562 LEUKEMIA CELL LINES", I. International Congress on Medicanal and Aromatic Plants ‘’Natural and Healthy Life’’, 2017. (Yayına Ulaşmak İçin Tıklayınız)
ULUSAL
37. KOÇYİĞİT SEVİNÇ SEVGİ,ORUN OYA,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Etodolak ve Türevlerinin Prostat Kanser Hücre Hattı Üzerine Sitotoksik Etkisi", 28.29. Ulusal Biyofizik Kongresi, 2017.
38. Kandemir Samed,MEGA TİBER PINAR,ORUN OYA, "Esansiyel Hipertansiyon Hastalarında Feniletanolamin N-Metiltransferaz Polimorfizmlerinin Belirlenmesi,", 28.29. Ulusal Biyofizik Kongresi, 2017.
39. BİRGÜL KAAN,uba abdullahi ibrahim,çuhadar ozan,KOÇYİĞİT SEVİNÇ SEVGİ,MEGA TİBER PINAR,ORUN OYA,yılmaz özgür,YELEKÇİ KEMAL,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "(S)-Naproksen’den Türeyen 1,2,4-Triazol ve Tiyoeter Bileşiklerinin Sentezi ve Meme Kanseri Üzerinde Antikanser Etkileri", 2. Ulusal Marmara Eczacılık Kongresi, 2018.
40. KOÇYİĞİT SEVİNÇ SEVGİ,ORUN OYA,MEGA TİBER PINAR,SÜZGÜN PELİN,KÜÇÜKGÜZEL ŞÜKRİYE GÜNİZ, "Cytotoxic effect of etodolac and Its derivatives on prostat cancer cell line", 28-29. Ulusal Biyofizik Kongresi, istanbul, 2017.
YAYINLANMAMIŞ BİLDİRİLER
ULUSLARARASI
1. ORUN OYA,MEGA TİBER PINAR,KOÇYİĞİT SEVİNÇ SEVGİ, "Cytotoxic effects of etodolac in breast cancer cell cultures", Ivek
2. KOÇYİĞİT SEVİNÇ SEVGİ,MEGA TİBER PINAR,ORUN OYA, "Gene regulations upon etodolac induced apoptosis in breast cancer cell cultures", IVEK
ATIFLAR
2018
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MAKALE
Belirtilmemiş
2018
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2018
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2018
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2018
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2018
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2018
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